GRM7 anticorps (pSer862)

N° du produit ABIN6658162

N° du produit (Fournisseur): 600-401-d78

L’anticorps Lapin Polyclonal anti-GRM7 a été validé pour WB. Il convient pour détecter GRM7 dans des échantillons de Rat.

Aperçu rapide pour GRM7 anticorps (pSer862) (ABIN6658162)

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRM7 anticorps

Épitope: pSer862

N° du produit (Fournisseur): 600-401-d78

Fournisseur: Rockland

Fonction: mGluR7 phospho S862 Antibody

Réactivité croisée (Details): Anti mGluR7 pS862 antibody is directed against mGluR7 phosphorylated at Ser862.

Purification: GluR7 antibody is affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: Anti-mGluR7 pS862 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 862 conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:1000

Commentaires:

Anti-mGluR7 pS862 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to the mGluR7 protein phosphorylated at Ser862 in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur GRM7

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Autre désignation: mGluR7

Sujet:

Synonyms: mGluR7, Metabotropic Glutamate Receptor 7

Background: mGluR7 pS862 antibodiy detects mGluR7 when phosphorylated at Ser862. Metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. The mGluRs are divided into three groups based on sequence identity and pharmacological properties: group I (mGluR1 and mGluR5) are localized in the perisynaptic region of the postsynaptic membrane, whereas group II (mGlur2 and mGluR3) and group III (mGluR4,6,7 and 8) are localized predominantly at presynaptic terminals. PKC phosphorylation of serine 862 on mGluR7 has been shown to be critical for stabilizing receptor surface expression and promoting binding to the synaptic PDZ-domain-containing protein PICK1. Therefore, mGluR7 pS862 antibody is ideal for investigators involved in neuronal circuitry and more generally in Neuroscience.

Gene Name: GRM7

ID gène: 81672

UniProt: P35400

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour